A/B Test Design: New Email Subject Line for Weekly Campaign
You manage a weekly email campaign to 10 million users. Baseline unique click-through rate (CTR) is 3.0% and unsubscribe rate is 0.08% per send. Marketing proposes a new subject line expected to increase CTR by +6% relative (≈ +0.18 percentage points absolute lift, from 3.00% to 3.18%).
Assume a single weekly send, independent Bernoulli outcomes at the user–send level, and that users can receive resends to non-openers and may be eligible for other campaigns in the same week unless controlled.
Design the experiment end-to-end:
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Randomization
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What is the randomization unit and what stratification blocks would you use (e.g., locale, device, engagement tier)?
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How do you prevent contamination from resends and cross-campaign overlap in the same week?
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Power
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Compute per-arm sample size for α = 0.05 (two-sided) and 80% power for detecting a +0.18 pp absolute lift on CTR from a 3.0% baseline.
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State assumptions and show the formula you would use.
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Metrics
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Choose a single primary success metric and at least two guardrail metrics (e.g., unsubscribe rate, spam complaints).
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Define each precisely (numerator/denominator, measurement window) and justify the choice over alternatives like open rate.
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Sequential Monitoring
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Leadership wants daily peeks and the ability to stop early for harm.
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Propose a valid plan (e.g., alpha-spending or group-sequential boundaries) that controls Type I error. Specify the monitoring schedule and stopping/continuation rules.
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Mid-Experiment Checks (at ~48 hours)
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What diagnostics would you run to detect randomization failure, instrumentation delays, or traffic mix shifts (e.g., weekend effects)?
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How would you correct issues without biasing estimates?
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Results Handling
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If an interim look shows negative CTR lift but higher opens, enumerate at least three plausible causes and the next decision (continue, stop-for-harm, or redesign).
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Explain how you would handle intention-to-treat vs per-protocol and what you would report to stakeholders.