The Data Scientist role at AbCellera sits at the intersection of high-throughput biology and advanced computational analysis. You are responsible for transforming massive, complex datasets—often derived from antibody discovery platforms—into actionable insights that drive drug development. By bridging the gap between raw experimental data and strategic decision-making, you play a pivotal role in accelerating the discovery of new medicines.
This position demands a unique combination of technical rigor and product-oriented thinking. You will not only build and maintain robust data pipelines but also design experiments and define the metrics that quantify the success of biological workflows. Because the work directly influences high-stakes R&D investments, your ability to communicate complex statistical concepts to non-technical stakeholders is just as vital as your proficiency in data manipulation.
Technical Screens
reportedBefore anything else, this round is a reading test. You are given a small schema and a question phrased in business language, and most of the difficulty sits in the gap between them. Who counts as an active user, does a refunded order still count as an order, is that date column an event time or a load time. Weak answers start typing immediately and compute something precise about the wrong population. Strong ones pin the definition in one sentence, name the column that encodes it, then write the query. On a timed assessment with nobody to tell, write the definition in a comment anyway.
What to demonstrate
- Whether an ambiguous term becomes a specific column and filter before any computation happens
- Whether you read the schema for keys and cardinality rather than only for column names
- Whether the result answers the question at the grain it was asked at, per user or per session or per day
How to prepare
- Take three metrics you already use and write down the exact filter and exact grain behind each, then practise stating one of them in a single sentence out loud
- On a schema you have never seen, spend the first minute writing what one row of each table means and which key it is unique on, then predict which joins can duplicate rows
- Rehearse a version where the definition changes halfway through, and edit the query you have instead of starting over
Deep-Dive Sessions
reportedAn extra round usually exists because something is still open after the standard loop: a skill the earlier interviews did not sample, a level decision, or two interviewers who disagreed. It is rarely a rerun of what you already did well. Ask the recruiter who you are meeting, what function they sit in, and how long the session runs. That is an ordinary scheduling question, and the answer changes what you should prepare. What separates a strong candidate here is treating the round as a fresh evaluation with its own bar, rather than assuming earlier performance carries you through or sinks you.
What to demonstrate
- Whether you can answer well on ground the earlier rounds did not cover, without leaning on what you already said to someone else
- Consistency of the facts in your stories: the same sample size, timeframe, team size and scope of your own role as in earlier conversations
- How you handle an unfamiliar format live, including whether you ask what kind of answer is wanted before producing one
How to prepare
- Ask the recruiter for the interviewer's function, the length, and whether to expect a coding surface, a discussion, or a presentation. Preparing for a 30 minute conversation with a partner team is not the same work as preparing for a 60 minute technical block.
- Write out what each earlier round actually covered, then list the two or three areas nobody probed. That gap is the most likely subject of the extra round.
- Re-read the numbers in the project stories you have already told, so a second telling does not quietly contradict the first.
Multi-Person Interviews
reportedRounds outside the standard loop often open with something deliberately under-specified: a loose business problem, an open question about a product area, a dataset described in one sentence. The common failure is surveying, listing six plausible approaches and committing to none of them. The thing that separates a strong answer is scoping out loud. State what you are treating as the goal, name the metric you would move, say what you are choosing not to do and why, then take one path through to an actual answer. An interviewer can follow you down a narrow path. Nobody can grade a menu.
What to demonstrate
- Whether you turn an ambiguous prompt into a stated question with a measurable outcome before doing any work
- The judgement visible in what you cut, and whether you say why you cut it rather than silently dropping it
- Whether you land on a concrete recommendation with its caveat attached, rather than an unranked set of options
How to prepare
- Take three vague prompts, such as 'is this feature working', 'why did retention drop', and 'should we expand into a new segment'. For each, write one sentence of goal, one primary metric with its window, and two things you are explicitly not doing.
- Practise giving the recommendation first and the reasoning second, in five minutes. Loosely defined rounds are usually time-boxed, and an answer that arrives last often does not arrive.
- Keep a running assumption list as you talk, on paper or in the shared doc, so the interviewer can challenge one assumption instead of your whole answer.
PracHub editorial advice for the preparation topics above.
Treating last-touch attribution as the causal value of a channel
The attribution label on dim_user is the output of a rule that assigns full credit to whichever touch happened to be recorded last inside a lookback window, and that rule systematically rewards channels that sit close to the conversion, especially branded search and retargeting, which largely intercept demand that already existed. Reallocating spend on those labels moves budget toward the channels that are best at being last, which is why attributed return on ad spend often improves while total signups do not. Nothing in the touchpoint data can settle this, because the counterfactual of not running the channel was never observed. The credible reads are a geo holdout or a scheduled pause, sized in advance on the total-signups metric rather than on the attributed one, and the honest framing in the meantime is that the label describes correlation with conversion and not incremental contribution.
Reading a pooled rate that moved because the mix moved, not because any behaviour changed
A pooled conversion rate is a weighted average, and a shift in the weights can move it in the opposite direction to every one of its parts. A paid campaign that brings low-converting traffic drops overall signup conversion even if desktop, mobile web and app conversion each rose that week, which is Simpson's paradox and it is the single most common cause of an inexplicable dashboard move. The discipline is to decompose before explaining: recompute the rate holding last period's segment weights fixed, and compare that counterfactual to the actual, so the mix effect and the rate effect are separated numerically rather than argued about. Segment on the dimensions that actually reweight, which in this domain are almost always device_type, referrer_channel, country and new versus returning.
Writing SQL without stating NULL and tie-breaking behaviour
Before calling a query finished, say what it does with NULLs, ties and empty groups. NOT IN against a subquery containing a single NULL returns no rows at all, and RANK, DENSE_RANK and ROW_NUMBER differ precisely on ties, so name which one the question requires.
Reading a dozen metrics with no multiplicity control
Nominate one primary metric before launch and treat the rest as guardrails or exploratory, with Bonferroni or Benjamini-Hochberg applied when you intend to make claims from them. Twenty independent tests at 0.05 under the null produce at least one false positive about 64 percent of the time.
Choose a category, try a prompt, then open its approach, worked solution or follow-up when you need it.
Implement seven-day activation from its written definition
Implement the seven-day activation rate. Inputs: dim_user with user_id, account_created_at_utc and is_internal; fct_event with user_id, occurred_at_utc and is_core_action. A user activates when core-action events carrying a non-NULL user_id fall on at least two distinct UTC dates inside [account_created_at_utc, account_created_at_utc + 7 days). The denominator is every non-internal user whose account_created_at_utc lands in the cohort week, including users with no events at all. Return one row per cohort week with numerator, denominator and rate, publishing only weeks whose last signup is at least eight days old.
Approach
- Build the denominator first, from dim_user alone, filtered on is_internal = False. Deriving it from the join is the standard way to lose every user who never fired an event, which is exactly the population the metric is about.
- Join events to users on user_id with a left join from the user side, then apply the window as a half-open interval: occurred_at >= created AND occurred_at < created + 7 days. The right bound is exclusive, so an event at exactly created + 7 days does not count.
- Count distinct UTC dates per user, not distinct events. Floor occurred_at_utc to date before the nunique, and do it in UTC rather than local time so the threshold does not move with the user's country.
- Apply the >= 2 threshold, aggregate to cohort week, and compute the rate by re-summing numerator and denominator per week rather than averaging any per-user or per-day rate. Fix the week anchor explicitly: cohort_week is the Monday of the signup week in UTC, which is what Postgres DATE_TRUNC('week') returns and what any SQL version of this metric will produce. In pandas, subtract dt.weekday days from the floored timestamp. If you reach for periods instead, the anchor that matches is to_period('W') (equivalently 'W-SUN'), whose weeks end Sunday and therefore start Monday; to_period('W-MON') labels weeks that end on Monday, so it runs Tuesday through Monday and its start_time is a Tuesday. Mixing the two shifts every cohort label by one day and silently moves Mondays into the previous week.
- Suppress immature weeks: drop any cohort week whose maximum account_created_at_utc is within 8 days of the data cut, and return them as absent rather than as a partial number.
Follow-up
- The threshold is 2 distinct days. What changes in the reported history if someone moves it to 3, and how would you publish that change?
- Invited seats and SSO-provisioned users have no pre-signup session. Should they be in this denominator at all, and what does including them do to the rate for sales-assisted accounts?
- How would you produce the same metric at account grain, and which of the two would you put on the dashboard?
Permutation test for a difference in conversion rates
Write a two-sided permutation test from scratch for a difference in conversion rates, using no scipy hypothesis function. Input: a DataFrame with unit_id, variant in {control, treatment} and converted in {0,1}, one row per randomisation unit. Compute the observed difference in proportions, then build the null distribution by reshuffling the variant labels while holding each arm's size fixed. Report the p-value as (1 + the count of permuted statistics at least as extreme in absolute value) / (B + 1) with B at least 10,000, and return the permutation distribution.
Approach
- Name the null being tested: the sharp null that each unit's outcome is the same under either label. That is what licenses permuting labels, and it is stronger than the null of equal means, which matters when someone asks whether the test is valid under unequal variances.
- Extract converted to a single numpy array of 0s and 1s and record n_treatment. Every permutation is then just a reshuffle of one array, and the treatment mean is the mean of the first n_treatment entries of the shuffled array.
- Vectorise the B permutations with rng.permuted on a tiled 2-D array, or with argsort of a (B, n) random matrix. A Python loop calling np.random.shuffle B times is correct but roughly an order of magnitude slower and often runs past the time limit.
- Use the +1 correction in both numerator and denominator. Without it a p-value of exactly 0 is reportable, which is false: the observed labelling is itself one of the permutations, so the smallest attainable p-value is 1/(B+1).
- Compare the resulting p-value against a two-proportion z-test as a sanity check. At these sample sizes they should agree closely; a large divergence means the statistic or the shuffle is wrong, not that the permutation test found something subtle.
Worked solution 25 min
- y = df['converted'].to_numpy(); n_t = (df['variant'] == 'treatment').sum(); obs = y[treat_mask].mean() - y[~treat_mask].mean().
- Build the null: for B draws, shuffle y and take the mean of the first n_t entries minus the mean of the rest.
- p = (1 + (np.abs(null) >= abs(obs) - 1e-12).sum()) / (B + 1), with the small tolerance so exact ties count as at least as extreme.
- Return obs, p and the null array; plot or describe the null to confirm it is centred at 0.
Follow-up
- The arms are 200 and 20,000 units. Does the permutation test stay valid, and what happens to its resolution at B = 10,000?
- Give a 95 percent confidence interval for the difference. Can you get it from this permutation distribution, and if not, what would you run instead?
- The randomisation unit is user_id but the outcome is per session. What breaks, and what is the fix?
Cluster bootstrap for a per-session rate randomised on users
An experiment randomised on user_id reports a per-session conversion rate, so sessions inside a user are correlated. Input: one row per session with user_id, variant in {control, treatment} and converted in {0,1}. Write a cluster bootstrap from scratch: resample users with replacement within each arm, keep every session of a drawn user, recompute each arm's ratio of converted sessions to sessions, and take the difference. Return the point estimate, a 95 percent percentile interval from at least 2,000 resamples, the naive session-level interval that ignores clustering, and the ratio of their widths.
Approach
- Name the estimand precisely: it is a ratio of sums, sum(converted) over sum(sessions) within an arm, not the mean of per-user rates. Those differ whenever session counts vary across users, and the ratio is what the reported metric is.
- Resample the cluster, not the row. Draw n_users user ids with replacement inside each arm and take every session belonging to each draw, including duplicate draws of the same user. Keeping the user count fixed per arm rather than the session count is what preserves the sampling design.
- Precompute per-user (converted_sum, session_count) once, so each resample is two vector lookups and a division rather than a repeated filter over the session frame. That turns 2,000 resamples from minutes into under a second.
- Take the 2.5th and 97.5th percentiles of the 2,000 differences for the interval, and report the point estimate from the full data rather than from the bootstrap mean, since the bootstrap mean carries the resampling bias.
- Compute the naive interval from the session-level binomial standard error and compare widths. The expected inflation is roughly sqrt(1 + (m-1)*rho), with m the mean sessions per user and rho the intraclass correlation of converted within users, so a computed ratio far from that value points at a bug in one of the two intervals.
Follow-up
- Users average 3.4 sessions and the intraclass correlation is 0.12. What width ratio do you predict before running it, and does your bootstrap land there?
- Give the delta-method standard error for this ratio and say when you would prefer it to the bootstrap.
- Half the users in the treatment arm have exactly one session. What does that do to the cluster bootstrap's coverage, and how would you check it?
Given a large dataframe, how would you perform a complex join to align…
Given a large dataframe, how would you perform a complex join to align disparate experimental results?
Approach
- Compute rates by summing numerator and denominator separately, never by averaging rates.
- State the window function and its partition and ordering out loud before writing it.
- Handle the rows that do not match: a LEFT JOIN with a NULL check is usually the question.
Follow-up
- How would you verify this result without re-running the same query?
- What breaks if events arrive late or out of order?
How would you use SQL window functions to track changes in experimenta…
How would you use SQL window functions to track changes in experimental results over time?
Approach
- Compute rates by summing numerator and denominator separately, never by averaging rates.
- Say which table is the grain you start from, and join outward from it.
- State the window function and its partition and ordering out loud before writing it.
Follow-up
- What breaks if events arrive late or out of order?
- How would you verify this result without re-running the same query?
Describe your approach to optimizing a costly database construction or…
Describe your approach to optimizing a costly database construction or query task.
Approach
- State the window function and its partition and ordering out loud before writing it.
- Compute rates by summing numerator and denominator separately, never by averaging rates.
- Say which table is the grain you start from, and join outward from it.
Follow-up
- How does the query change if the join becomes one-to-many?
- How would you verify this result without re-running the same query?
Find reactivation gaps in account paid-period history
fct_subscription_period holds account_id, subscription_id, period_start_utc, period_end_utc, period_status and change_reason. A mid-period plan or seat change closes one row and opens another, so a single continuous paid tenure is often many rows, and an account may hold two overlapping subscriptions. Collapse rows with period_status in ('active','past_due') into continuous tenures per account, treating gaps of three days or less as continuous. Return account_id, tenure_start, tenure_end, and for every tenure after the first, the gap in days that preceded it.
Approach
- Filter to paid rows only: period_status IN ('active','past_due'). Trialing periods are not tenure, and including them turns every trial that never converted into a one-period tenure followed by a fake churn.
- Order by period_start_utc and take a running maximum of all prior ends: MAX(period_end_utc) OVER (PARTITION BY account_id ORDER BY period_start_utc, period_end_utc, subscription_id ROWS BETWEEN UNBOUNDED PRECEDING AND 1 PRECEDING). Those three columns are the only stable ordering this schema exposes, so check first that they are unique within an account; if rows tie on all three, the island numbering is order-dependent between runs and you need a real row key before the result is reproducible.
- LAG on its own is wrong here because with overlapping or nested periods the immediately preceding row by start date is not the one that ends latest, so the running maximum is the part that cannot be shortcut.
- Flag a new island when prior_max_end IS NULL OR period_start_utc > prior_max_end + interval '3 days', then number islands with a running SUM of the flag over the same ordering and an explicit ROWS frame.
- Group to (account_id, island) taking MIN(period_start_utc) and MAX(period_end_utc), then LAG(tenure_end) OVER (PARTITION BY account_id ORDER BY tenure_start) to compute the preceding gap in days for every tenure after the first.
- Sanity-check with change_reason, which is the only lineage this schema carries: list its distinct values first, then confirm that rows recording a plan or seat change sit inside a tenure rather than opening one, and that every tenure after the first opens on a row whose reason records a restart rather than an ordinary renewal. Do not reconcile against a churn timestamp on dim_account, which this schema does not define; and where such a column does exist, a cancellation timestamp records when the request was made and routinely sits weeks before the period it ends.
Worked solution 35 min
- Find an account with a known mid-period upgrade and dump its period rows to use as the trace case.
- Check that (period_start_utc, period_end_utc, subscription_id) is unique per account, since the whole ordering rests on it.
- Write the paid-rows CTE and the running MAX with the explicit frame.
- Add the island flag and the running SUM, then verify the trace account yields one island.
- Group to tenures and add the LAG-based gap in days.
- List the distinct change_reason values, then count accounts with more than one tenure and compare against the count of accounts carrying a restart-flavoured reason anywhere in their history.
Follow-up
- Why three days of grace? What do 0 and 30 days each do to the count of accounts classed as reactivated?
- An account runs two concurrent subscriptions for different teams. One tenure or two, and what does the revenue reader expect?
- How would you turn these tenures into a monthly gross logo churn series without double-counting an account that churned and returned in the same month?
How do you balance the trade-offs between speed and accuracy when desi…
How do you balance the trade-offs between speed and accuracy when designing a new product feature?
Approach
- Decompose the metric into the rates that drive it, and say which one you would check first.
- Restate the decision this analysis has to support, and who acts on the answer.
- State what result would change your recommendation, so the answer is falsifiable.
Follow-up
- How would you detect that the metric is being gamed rather than genuinely improving?
- Which segment would you cut first, and what would that rule out?
If we notice a sudden drop in our key performance metric, what is your…
If we notice a sudden drop in our key performance metric, what is your step-by-step process for diagnosing the root cause?
Approach
- Name one primary metric, then the guardrail that stops it being gamed.
- Fix the population and the time window before naming any metric.
- State what result would change your recommendation, so the answer is falsifiable.
Follow-up
- What would you do if the primary metric and the guardrail moved in opposite directions?
- Which segment would you cut first, and what would that rule out?
How would you design a metric to measure the success of a new high-thr…
How would you design a metric to measure the success of a new high-throughput screening process?
Approach
- Name one primary metric, then the guardrail that stops it being gamed.
- Restate the decision this analysis has to support, and who acts on the answer.
- Decompose the metric into the rates that drive it, and say which one you would check first.
Follow-up
- Which segment would you cut first, and what would that rule out?
- How would you detect that the metric is being gamed rather than genuinely improving?
How do you decide between a frequentist and a Bayesian approach for a …
How do you decide between a frequentist and a Bayesian approach for a new experiment?
Approach
- Say whether units interfere with each other, and switch design if they do.
- Name the randomisation unit first; it decides the variance and what the test can detect.
- Name the guardrails that would stop a launch even on a positive primary result.
Follow-up
- What would you conclude if the result is positive but the test is underpowered?
- What would you do if you could not randomise at all?
What are the common experimentation pitfalls that lead to false positi…
What are the common experimentation pitfalls that lead to false positives?
Approach
- Name the guardrails that would stop a launch even on a positive primary result.
- Decide the analysis before seeing data, including how long it runs and when you look.
- Say whether units interfere with each other, and switch design if they do.
Follow-up
- What would you conclude if the result is positive but the test is underpowered?
- How would you handle interference between treated and control units?
A completion rate the owning team can move without fixing anything
A team's target is core-flow completion rate: distinct fct_event.flow_instance_id with a 'flow_completed' event within 30 minutes of its 'flow_started' and no 'error_shown' carrying the same flow_instance_id in between, over distinct flow_instance_id with a 'flow_started' in the window, split by surface and app_version. The same team owns the client that emits those events and the tracking plan that defines them. List the ways this rate rises without any user completing more flows, then redefine the metric and its guardrails so those routes are closed. Deliverable: the hardened definition.
Approach
- Work the emission side first, because that is what the team controls: delay minting flow_started until after the first screen so the highest-dropping attempts leave the denominator; stop emitting or rename error_shown; mint a fresh flow_instance_id on each retry so one failed attempt becomes several attempts whose last one completes; move flow_completed earlier in the flow.
- Sort those moves by where they are visible. None of them shows in the rate itself; three of them show only in volume, which is why the denominator has to be published on the same chart as the rate.
- Re-anchor the numerator on something outside the flow's own instrumentation: require a downstream is_core_action = TRUE event for the same user_id within 30 minutes of flow_completed, so a completion only counts when it produced the thing the flow exists to produce.
- Add the guardrail that catches the retry route specifically: mean and p90 flow_instance_id per user per day, with the rule written down that a rising completion rate alongside rising attempts per user is a regression and not a win.
- Make definition changes visible instead of forbidden: stamp a tracking-plan version on the series and re-base the history when event semantics or the 30-minute window change, rather than splicing two definitions into one line.
Worked solution 25 min
- Enumerate at least four emission-side moves and mark for each whether it shows in the rate or only in volume.
- Pin the denominator: publish flow_started per 1,000 sessions and per distinct user beside the rate.
- Rewrite the numerator to require a downstream core action for the same user within 30 minutes.
- Add the attempts-per-user guardrail with its interpretation rule stated as a sentence.
- Version the definition and write the re-base policy for the historical series.
Follow-up
- How do you distinguish a genuine instrumentation fix from gaming, given both look like a step change confined to one release?
- The jump appears in exactly one app_version. Does that exonerate the team or implicate it?
- What do you do with eighteen months of history once the definition is hardened?
Tell a pipeline outage from a collapse in usage
Weekly active accounts completing a core action fell 9%, and almost the entire fall sits in accounts whose events carry surface = 'ios'. App crash rates and store reviews are unchanged. You have fct_event with occurred_at_utc, received_at_utc, event_name, is_core_action, app_version and surface, plus fct_session and the ingestion job run log. Establish within the hour whether iOS engagement fell or iOS events stopped arriving, name the evidence that distinguishes them, and say what you would publish on the dashboard in the meantime.
Approach
- Compare the event-name composition inside surface = 'ios' against the prior four weeks as shares, not counts. A behaviour collapse scales most event names together; a dropped event definition or a broken downstream filter hits specific event_name values while page_view and session-opening events hold steady. That shape difference is the fastest discriminator available.
- Profile the received_at_utc minus occurred_at_utc distribution per day for surface = 'ios'. A stalled-then-backfilling pipeline shows a fat upper tail and a recovering p99; a silently dropped stream shows an unchanged lag distribution over a smaller volume. The two failure modes have different remedies and different histories.
- Cut by app_version. A logging SDK change arrives with one build and ramps with its adoption curve; an infrastructure fault arrives across every build within the same hour. Checking this costs one group-by and rules out half the hypothesis space.
- Cross-check against a signal that does not travel the suspect path: server-emitted events with session_id NULL, and subscription or billing activity for the same accounts. If those accounts are still transacting, the users did not leave.
- Publish an ex-iOS total with an explicit annotated break rather than a blended total. A blended number during a known ingestion gap is wrong in a direction you can already name, and republishing it daily spreads the artefact into every downstream report.
Follow-up
- Suppose the events do eventually backfill. What is your policy for restating the published weekly numbers, and who needs to be told?
- What monitor would have caught this before a human noticed the weekly metric, and what would it alert on?
- If is_core_action is maintained in the tracking plan, what governance would stop a change to that list from silently moving a north-star metric?
For someone who has spent the last year in notebooks, dashboards or modelling work and has not written raw SQL under time pressure. The first four days rebuild query fluency against a fixture you control and can verify by hand; the last three attach that fluency to the rest of the loop.
Prepare, practise & reflect
One practical outcome each day. Spend longer where you need it.
0 / 7 done01Build a fixture you can check answers against
- Create a local Postgres or SQLite database with four tables (users, sessions, events, orders) holding roughly 200 rows you generated yourself, so you know the contents well enough to predict every result.
- Deliberately seed the cases that break queries: a user with no sessions, a session with no events, two orders sharing a timestamp, a NULL in one join key, and one duplicated user row.
- Before writing any SQL, hand-compute five answers on paper (how many users placed at least one order, median orders per ordering user, and three others) and save them as the ground truth for the week.
Deliverable: A one-command seed script plus a text file of five hand-computed answers to grade every later query against.
Practice prompt ↗Practice prompt ↗Practice prompt ↗Worked solution ↗02Joins, filters and NULL semantics
- Answer "which users have no orders" three ways (LEFT JOIN with IS NULL, NOT EXISTS, NOT IN) and confirm that the NOT IN version returns zero rows once the subquery contains a NULL, because the comparison is never TRUE.
- Reproduce the LEFT JOIN that silently collapses to an inner join by putting a right-table predicate in WHERE, then fix it by moving the predicate into the ON clause, and record both row counts.
- Create a fan-out bug on purpose by joining orders to order_items and summing the order total, then correct it with a pre-aggregated subquery and explain in one line which table changed the grain.
Deliverable: One annotated .sql file holding the three join traps, each with the wrong result and the corrected result side by side.
Practice prompt ↗Practice prompt ↗Practice prompt ↗03Window functions and frames
- Write three window queries against the fixture: a running order total per user, the rank of each order within its user by value, and the day gap to that user's previous order, then check each against the day-one ground truth.
- Run ROW_NUMBER, RANK and DENSE_RANK over a column containing ties, print all three side by side, and write one sentence on when each is the correct choice.
- Switch one query from the default frame (RANGE BETWEEN UNBOUNDED PRECEDING AND CURRENT ROW, which is what you get when ORDER BY is present and no frame is written) to ROWS BETWEEN UNBOUNDED PRECEDING AND CURRENT ROW, and explain why the output differs only when the ORDER BY column has duplicates.
Deliverable: Three verified window queries plus a short note explaining the RANGE versus ROWS difference in your own words.
Practice prompt ↗Practice prompt ↗Practice prompt ↗04The four analytical query patterns
- Write a monthly retention grid: first order month per user, then months-since-first as the column, and verify that month zero equals the cohort size exactly.
- Sessionize the events table under a 30-minute inactivity rule using LAG plus a cumulative sum over a new-session flag.
- Build a four-step funnel that counts distinct users rather than events at each step, and state the rule you applied to a user who reaches step three without ever logging step two.
Deliverable: One file with the retention, sessionization and funnel patterns, each carrying a one-line note on the assumption it bakes in.
Practice prompt ↗Practice prompt ↗Worked solution ↗05Write SQL the way you will have to write it live
- Set a 12-minute timer and solve three medium prompts in a plain editor with no execution and no autocomplete, then run them and tally syntax errors separately from logic errors.
- Narrate one solution aloud while writing it, stating the grain of each intermediate result (one row per user, one row per user-day) before you type its body.
- Rewrite your slowest solution as a CTE chain where every CTE name states its grain, and time yourself re-solving it from blank.
Deliverable: A recording of one narrated solution plus an error tally that separates syntax from logic.
Practice prompt ↗Practice prompt ↗06One day for everything that is not SQL
- Write the preconditions of the two-sample t-test from memory, then check them: independent observations, and a difference in means whose sampling distribution is approximately normal, which at large sample sizes follows from the central limit theorem rather than from normality of the raw values.
- Write the difference between an odds ratio from logistic regression and a relative risk, and state the condition under which the two are close (low outcome prevalence).
- Prepare a 90-second answer to "how would you know this model is any good" that names the metric, the baseline you would beat, and the cost of the errors you care about.
Deliverable: One page of notes covering test preconditions, the odds-ratio caveat and the model-quality answer.
Practice prompt ↗Practice prompt ↗07Full loop rehearsal
- Run a 45-minute mock with someone willing to interrupt: 20 minutes of SQL, 15 minutes defining a metric, 10 minutes on a past project.
- Re-solve from blank the two queries you were slowest on this week and compare the times against day five.
- Write a five-line answer to "walk me through a project" that puts a number in the first sentence and names the decision the work changed.
Deliverable: Mock feedback notes plus a timed project narrative you can deliver without reading it.
Practice prompt ↗Practice prompt ↗Worked solution ↗Expand any day for tasks and deliverables. Your progress is saved on this device.
Interviewers here are not checking whether you can describe a project. They want the decision you made, why you made it under the information you had, and what changed afterwards that someone else could measure. A story that ends at 'I built a model' has no ending. Say what the model caused, or what you stopped doing because of it.
Explain the concept of power analysis to a non-technical stakeholder.
Explain the concept of power analysis to a non-technical stakeholder.
Approach
- Name the disagreement or constraint, and how you resolved it with evidence.
- Quantify the outcome, including what you would not claim credit for.
- Close with what you would do differently, concretely.
Follow-up
- How did you know the outcome was caused by your change?
- What would you do differently if you ran that project again?
Defend a flat experiment readout against a post-hoc segment
A feature you evaluated is flat on seven-day activation: +0.05pp with a 95% interval of [-0.47pp, +0.57pp], from 61,000 exposed users per arm in fct_experiment_exposure joined to dim_user and fct_event. Baseline activation is 32%. The launch team asks you to drop every surface except mobile_web, where the point estimate is +1.1pp, and re-run. You have ten minutes in their planning meeting. Deliver a spoken position: what you will and will not do, and the decision you recommend.
Approach
- Recognise what is being probed: whether you hold a statistical position under social pressure without becoming either rigid or apologetic. A generic answer says the segment is not significant; a strong one separates the request into a question that is answerable (is the mobile_web number real?) and one that is not (can we ship on it?), and answers both.
- Price the multiplicity out loud. The slice was chosen after seeing the results, so its estimate is selected on favourable noise and is biased away from zero. With k independent looks at a nominal 5% level, the chance of at least one false positive is 1 - 0.95^k: 26% at six segments, 64% at twenty. Quote the k you actually inspected, not the k you reported.
- Use the arithmetic already in front of you. On the point estimates, a +1.1pp mobile_web effect combined with a pooled +0.05pp implies the remaining surfaces average negative in proportion to mobile_web's share of exposures. State that as a testable implication of their story rather than as a rebuttal of it.
- Ask the one question that settles the category: was mobile_web named in the analysis plan before launch? If it was, it is a planned comparison and gets a corrected reading. If it was not, it is a hypothesis, and the honest move is to size the test that would confirm it.
- Convert the refusal into a cost. Size a mobile_web-only confirmatory test at the claimed effect, state the weeks of mobile_web traffic it needs, and close with the recommendation: do not ship this as a lift, and note that the interval already rules out anything at or above +0.6pp, which is itself a useful input to the roadmap.
Follow-up
- The confirmatory test you sized needs nine weeks of mobile_web traffic and the team has three. What do you recommend instead?
- Suppose mobile_web was pre-registered. How does your reading change, and what correction do you apply?
- Your interval excludes +0.6pp. Is that the same as saying the feature does nothing?
Explain a wide interval to a non-technical executive
A pricing change is under consideration. Your best estimate of its effect on trial-to-paid conversion is a 1.8pp drop, with a 95% interval from a 4.6pp drop to a 1.0pp rise, read from a geo holdout rather than a randomised test. An executive preparing a board slide asks you for 'the number'. You have ninety seconds and one slide, and the words confidence interval, p-value and significance are not usable with this audience. Deliver the slide headline, the single supporting line, and what you say aloud.
Approach
- Recognise what is being probed: whether you can carry uncertainty into a decision instead of either hiding it or hiding behind it. The generic answer promises to explain the interval in plain English; the strong one replaces the question 'what is the number' with 'across this range, where does the decision change'.
- Find the threshold before you draft anything. Ask what the pricing case assumes, then compute the conversion drop at which the higher price stops adding revenue: price uplift on the conversions kept against the revenue lost from conversions forgone. That single figure is what makes the range legible.
- Restate the estimate and both bounds in the unit the audience already reasons in. Convert percentage points into monthly first-paid conversions at current trial volume, then into mrr_cents_constant_fx, so the slide reads as money per month rather than as statistics.
- Place the range against the break-even and say which part of it sits on each side. If most of the range clears the threshold, that is a recommendation to proceed with a monitoring plan; if the range straddles it, that is a recommendation to narrow the range first.
- Name what would narrow it and what that costs in weeks, then give one recommendation with an explicit condition for revisiting it. Uncertainty stated without a next step is read as indecision and the midpoint gets used anyway.
Follow-up
- The executive says to give the midpoint and they will manage the risk. What do you do?
- How does the slide change if the interval were a 4.6pp to 0.2pp drop, with no positive outcomes in range?
- Why is a geo holdout the credible read here rather than the attributed channel numbers you already have?
- 01
Explain the concept of power analysis to a non-technical stakeholder.
- 02
A feature you evaluated is flat on seven-day activation: +0.05pp with a 95% interval of [-0.47pp, +0.57pp], from 61,000 exposed users per arm in fct_experiment_exposure joined to dim_user and fct_event. Baseline activation is 32%. The launch team asks you to drop every surface except mobile_web, where the point estimate is +1.1pp, and re-run. You have ten minutes in their planning meeting. Deliver a spoken position: what you will and will not do, and the decision you recommend.
- 03
A pricing change is under consideration. Your best estimate of its effect on trial-to-paid conversion is a 1.8pp drop, with a 95% interval from a 4.6pp drop to a 1.0pp rise, read from a geo holdout rather than a randomised test. An executive preparing a board slide asks you for 'the number'. You have ninety seconds and one slide, and the words confidence interval, p-value and significance are not usable with this audience. Deliver the slide headline, the single supporting line, and what you say aloud.
Is this an official AbCellera interview guide?
No. It is PracHub's own research and practice material for the Data Scientist role at AbCellera. Rounds and questions reflect what candidates have reported, not a process AbCellera has published, and they change over time. Confirm the current format and scope with your recruiter.
PracHub interview research ↗How difficult are the technical interviews?
The technical rounds focus on practical application rather than theoretical brainteasers. If you are comfortable with real-world data manipulation and basic statistical concepts, you will find the difficulty level to be manageable.
PracHub interview research ↗What is the best way to stand out?
Successful candidates distinguish themselves by showing genuine curiosity about AbCellera’s mission and by clearly articulating the "why" behind their technical choices.
PracHub interview research ↗How long is the interview process?
The process varies depending on the team and role level, but you should expect a multi-week engagement.
PracHub interview research ↗Can I expect remote work?
Expectations around location depend on the specific team and role; confirm this during your initial recruiter screen to ensure alignment.
PracHub interview research ↗Sources & methodology 3 sources ↗
No official company page is cited. Rounds and questions come from candidate reports and PracHub editorial material; each source shows the date it was read.
- 01PracHub interview research ↗
PracHub editorial research into this company and role, maintained with this guide. Candidate-reported, not an employer publication.
PracHub page · Accessed 2026-09-22 - 02PracHub Data Scientist practice ↗
Cross-company practice questions for this role.
PracHub page · Accessed 2026-09-22 - 03PracHub interview preparation framework ↗
The framework the preparation plan follows.
PracHub page · Accessed 2026-09-22
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