Tempus AI · Data Scientist
Updated · 2026-09-22

Tempus AI Data Scientist
Interview Questions & Guide 2026

THE 60-SECOND BRIEF

This guide covers what a Data Scientist at Tempus AI is expected to do and how to prepare for the interview.

SQL is seldom the hardest round and is often the one that eliminates people. The working bar is usually window functions, correct deduplication, and joins that do not silently fan out rows, rather than obscure syntax.

Tempus AI candidates report 3 rounds · ≈ 3-5 weeks. The stages below are what candidates describe, not a published process.

Risk-adjust outcomes before comparing providers or panelsCorrect for claims runout before reporting recent monthsSeparate censoring from events in time-to-event models

32 min read

Browse Data Scientist questions

See the practice prompts

18Practice promptsAcross five skill areas
3With worked solutionsIncluded in the practice prompts

This guide covers what a Data Scientist at Tempus AI is expected to do and how to prepare for the interview.

01

Recruiter Screen

reported

Data Scientist covers at least four different jobs: experimentation, product analytics, causal work on observational data, and applied modelling that ships into a system. A screening call is the cheapest place to find out which of them is being hired for, and doing that diagnosis openly reads as senior rather than fussy. Ask what the last few pieces of work on the team actually were, and roughly how a week splits between querying, modelling and stakeholder time. Then say which parts of that you have done and which you have not. Claiming the whole range is the fastest way to be caught one round later.

What to demonstrate

  • Whether you can distinguish the flavours of the role and locate your own experience inside one of them honestly
  • Whether you name what you have not done instead of stretching to cover every line of the posting
  • Whether your hard constraints (notice period, location, work authorisation, level) surface now rather than at offer stage

How to prepare

  • Map the last two years of your time into rough percentages across query writing, experiment design, modelling and stakeholder work, so a question about scope has a real answer
  • Mark every responsibility in the posting as done, adjacent or new, and prepare one sentence for each adjacent item naming the closest thing you have actually built
  • Decide which logistics are non-negotiable before the call so you can state them in one sentence rather than negotiating live
PracHub interview research ↗
02

Technical Screen

reported

Before anything else, this round is a reading test. You are given a small schema and a question phrased in business language, and most of the difficulty sits in the gap between them. Who counts as an active user, does a refunded order still count as an order, is that date column an event time or a load time. Weak answers start typing immediately and compute something precise about the wrong population. Strong ones pin the definition in one sentence, name the column that encodes it, then write the query. On a timed assessment with nobody to tell, write the definition in a comment anyway.

What to demonstrate

  • Whether an ambiguous term becomes a specific column and filter before any computation happens
  • Whether you read the schema for keys and cardinality rather than only for column names
  • Whether the result answers the question at the grain it was asked at, per user or per session or per day

How to prepare

  • Take three metrics you already use and write down the exact filter and exact grain behind each, then practise stating one of them in a single sentence out loud
  • On a schema you have never seen, spend the first minute writing what one row of each table means and which key it is unique on, then predict which joins can duplicate rows
  • Rehearse a version where the definition changes halfway through, and edit the query you have instead of starting over
PracHub interview research ↗
03

Onsite Interview

reported

A loop is not scored one interview at a time. The people you meet compare notes afterwards, usually in a meeting you are not in, and the outcome turns on what each of them can say about you when asked. That rewards something other than survival: every room needs one specific thing worth repeating, and none of them can contradict another. The common way to lose is to tell the same project four times with different numbers in it, or to be uniformly fine in a way that leaves nobody with anything to argue for.

What to demonstrate

  • Whether your account of a project survives being told twice, with the same scale, the same metric definition and the same numbers each time
  • Whether each interviewer leaves with one concrete claim they could make on your behalf later, rather than an absence of complaints
  • Whether a question you already answered in an earlier room gets the same answer at the same depth, without visible impatience

How to prepare

  • Write a one-page fact sheet for your two or three main projects that fixes the numbers you will quote: rows of data, the metric as a single sentence, the effect you measured and how long the work took. Say them aloud from the sheet until they come out identical every time
  • For each kind of room you expect, decide the one sentence you want that interviewer repeating in a debrief, then check during the mock that you said it outright instead of implying it
  • Rehearse answering the same project question twice in one sitting, the second time as though you had not just answered it, because the thing that needs fixing is the flatness that creeps into a repeated story
PracHub interview research ↗

PracHub editorial advice for the preparation topics above.

01

Rates built on member counts rather than exposure

Members join and leave mid-period, so dividing events by distinct members mixes a person covered for 30 days with one covered for 365. New joiners also have artificially low observed utilisation because their claims have not arrived yet and because care takes time to initiate. Denominators must be member-months or member-years, and comparative quality measures usually need a continuous-enrolment requirement with an explicit allowable gap, stated in days.

02

Ignoring clustering by provider, facility, or site

Patients within a provider panel, and subjects within a trial site, are correlated on both case mix and practice pattern. Standard errors computed as if observations were independent are too narrow by roughly the design effect, 1 + (m - 1) * ICC, where m is the average cluster size. With 50 patients per provider and an intracluster correlation of only 0.02, variance is understated by about a factor of two, which manufactures significant provider differences out of noise. Cluster-robust errors or a random intercept per provider, and cluster-level randomisation when you design the test, are the corrections.

03

Stopping an experiment the moment it crosses significance

Fix the sample size or duration before launch, or use a method built for continuous monitoring such as a sequential test, always-valid confidence intervals, or group-sequential boundaries. Repeatedly checking a fixed-horizon p-value against 0.05 pushes the real false-positive rate well above 5 percent.

04

Analysing at a different unit than the one randomised

Say out loud what was randomised (user, device, account, cluster) and make the analysis unit match, or account for the clustering with cluster-robust standard errors, the delta method, or aggregation up to the randomised unit. Randomising users and then running a test over sessions understates variance and inflates the false-positive rate.

Choose a category, try a prompt, then open its approach, worked solution or follow-up when you need it.

15 technical prompts3 include a worked solution

How do you approach survival analysis and time-to-event methodologies …

medium
statistics and probability

How do you approach survival analysis and time-to-event methodologies when dealing with censored real-world clinical data?

Approach
  1. Quantify uncertainty explicitly rather than reporting a point estimate alone.
  2. Sanity-check the answer against a simple bound or a simulated case.
  3. Translate the result into the decision it informs, in one plain sentence.
Follow-up
  • How would you explain this result to someone who does not know statistics?
  • Which assumption here is most likely to be violated in practice?

How do you define and track data drift for machine learning models dep…

medium
machine learning and modelling

How do you define and track data drift for machine learning models deployed in production clinical environments?

Approach
  1. Check what information would not exist at prediction time, and exclude it.
  2. Set a baseline first, so any model has something honest to beat.
  3. Frame the prediction: the label, the moment of prediction, and the action it triggers.
Follow-up
  • How would you choose the decision threshold, and who owns that choice?
  • What would you monitor after launch to know the model is still valid?

Collapse claim versions before summing allowed amounts by member

easyWorked solution
claim versioninggroupbydeduplication

You are given medical_claim_line as a pandas DataFrame: claim_line_id, claim_id, claim_version, frequency_code (1 original, 7 replacement, 8 void), member_id, service_start_date, procedure_code, allowed_amount, claim_status. Return total allowed_amount per member for service dates in one stated calendar month, counting each claim once at its surviving version and excluding any claim whose surviving version is a void. Multi-line claims must keep every line of that surviving version. Output columns: member_id, allowed_amount, sorted descending. Do not deduplicate on claim_id alone.

Approach
  1. Separate the two grains out loud before writing code: versions live at the claim level, dollars live at the line level. Every bug in this exercise comes from mixing them.
  2. Compute the surviving version per claim with a groupby transform of max over claim_version, then keep the lines whose claim_version equals that value. A transform keeps the frame at line grain, which a sort plus head(1) does not.
  3. Drop whole claims whose surviving version carries frequency_code 8. A void is not a zero-dollar line, it retracts the claim, so filtering rows rather than claims leaves the prior version's lines behind.
  4. Filter to claim_status 'paid' and state the assumption: denied, pended and reversed lines carry an allowed_amount that never became a liability, so including them overstates cost.
  5. Restrict service_start_date to the month boundaries, then groupby member_id and sum. Sort descending and return.
Worked solution 20 min
  1. Build a max-version lookup per claim_id with groupby('claim_id')['claim_version'].transform('max') and keep rows where claim_version equals it.
  2. From the surviving rows, collect the claim_ids whose frequency_code is 8 and drop those claim_ids entirely.
  3. Filter claim_status to 'paid' and service_start_date into the month window.
  4. Group by member_id, sum allowed_amount, sort descending, reset the index.
EXPECTED RESULTA two-column frame member_id, allowed_amount. On a claim with versions 1, 7, 7 only the third version's lines contribute; a claim whose latest version is frequency_code 8 appears nowhere. Total allowed is strictly below a naive sum over all rows whenever any claim in the sample was adjusted, and equal to it when none was.
Follow-up
  • A claim has versions 1, 7, 7 where the second replacement has fewer lines than the first. What does your code return and is that correct?
  • How would you handle a claim whose lines span two calendar months at the boundary of the reporting window?
  • The same logic has to run over 400 million lines in a warehouse. What changes, and what stays the same?

Roughly 90 minutes a night on weekdays with one longer weekend block. The plan deliberately cuts scope rather than compressing everything, on the assumption that finishing one thing a night beats half-starting four.

Small steps. Visible outcomes.0 / 7 completed
ONE WEEK · YOUR PACE

Prepare, practise & reflect

One practical outcome each day. Spend longer where you need it.

0 / 7 done
01Fix the scope and set a baseline
  • Read the role description and write the three things the loop will almost certainly test, then write an explicit not-doing list for everything else and keep it visible all week.
  • Take one 20-minute SQL prompt and one 10-minute metric question cold, and write the single sentence that says what blocked each attempt, since that sentence is what decides which two topics get the most evenings.
  • Set the week's one rule: one problem finished to completion every night, including the night you only have 40 minutes.

Deliverable: A one-page scope with an explicit not-doing list and two cold attempts, each carrying one sentence on what blocked it.

Practice prompt ↗Practice prompt ↗Practice prompt ↗Worked solution ↗
02One query pattern, written three times
  • Choose the single pattern most likely to appear (a cohort retention grid, or a funnel counted by user) and write it three times from a blank file rather than editing the previous attempt.
  • On the third attempt, write the grain of every CTE as a comment before writing its body.
  • Stop at 90 minutes even if the third version is imperfect, and write the one thing you would fix with another hour.

Deliverable: Three independent versions of the same query plus a note on what changed between them.

Practice prompt ↗Practice prompt ↗Practice prompt ↗
03Only the statistics you will be asked to defend
  • Write, in under 200 words, how you would decide whether a difference between two groups is real: the test, its assumptions, and what you would switch to when an assumption fails.
  • Compute a 95 percent confidence interval for a difference in proportions by hand on realistic numbers, then write in one sentence what changes if the two samples are paired rather than independent.
  • Write your answer to "what does a p-value mean", check it against a definition, and delete the version that describes it as the probability the hypothesis is true.

Deliverable: A 200-word written answer and one hand-computed interval you can reproduce under pressure.

Practice prompt ↗Practice prompt ↗Practice prompt ↗
04One case, and the assumptions holding it up
  • Answer one product case aloud in 20 minutes with a recording running, then listen back with a pen and mark every claim you asserted without saying what it rested on: an assumed user behaviour, an assumed data source, an assumed baseline rate, an assumed grain.
  • Pick the three assumptions the recommendation actually depends on, write how you would check each one against data, and say which one being wrong would flip the recommendation rather than merely weaken it.
  • Write the four-step structure you used onto a card small enough to hold in working memory when you are nervous.

Deliverable: One recording, three load-bearing assumptions each with a written check, and a four-step structure card.

Practice prompt ↗Practice prompt ↗Practice prompt ↗Worked solution ↗
05Your own work, timed
  • Write a 90-second version and a four-minute version of your main project, and time both out loud rather than reading them.
  • Prepare answers to the two follow-ups that always come: what you would do differently, and how you knew it worked.
  • Put one number in the first sentence and be able to say exactly where that number came from and what it excludes.

Deliverable: Two timed narratives with one defensible number in the opening line.

Practice prompt ↗Practice prompt ↗
06The one full rehearsal, in a longer weekend block
  • Run a 60-minute mock covering query work, a case and a behavioural question in a single sitting with no breaks, because sustained attention is the thing evenings have not trained.
  • Immediately afterwards, and before hearing any feedback, write the three moments you lost the thread.
  • Spend the rest of the block only on those three moments, and on nothing you merely feel shaky about.

Deliverable: Mock notes naming three failure moments with a specific fix written under each.

Practice prompt ↗Practice prompt ↗
07Taper
  • Write the 20-minute warm-up you will actually do on the morning of the interview: one query you can already write from a blank file, one metric you can define out loud, and nothing you have never seen before.
  • Re-read only your own notes from this week, and open no new material.
  • Write down the logistics: the tool you will be asked to work in, whether lookups are allowed, and the sentence you will use when you do not know something.

Deliverable: A one-page card holding the case structure, the project numbers, and the logistics.

Practice prompt ↗Practice prompt ↗Worked solution ↗

Expand any day for tasks and deliverables. Your progress is saved on this device.

An answer without a quantity is hard to interrogate, so interviewers keep probing until they find one. Come with the baseline, the change, the window it was measured over, and how confident you were. If the effect never got measured, say so and say what you would have measured. Fabricated precision is worse than an honest gap.

Describe a situation where your initial analysis or hypothesis was pro…

medium
behavioural and stakeholder questions

Describe a situation where your initial analysis or hypothesis was proven wrong. How did you pivot and communicate this to your team?

Approach
  1. Close with what you would do differently, concretely.
  2. Quantify the outcome, including what you would not claim credit for.
  3. Pick a story where you drove the decision, not one where you observed it.
Follow-up
  • What would you do differently if you ran that project again?
  • What did you decide not to do, and why?

Make an honest case for your own analytical impact

hard
impact attributioncounterfactualself-assessment

You are asked to account for a year of your work. Constraint: you may only use measures that existed before you knew the outcome, and you must include one project that moved nothing. The portfolio contains a measure specification that changed how a contract settles, a predictive model that shipped, a self-serve dashboard, and an evaluation that killed a proposed programme. Deliverable: how you attribute value to each, which of them you claim credit for and which you do not, and the one number you would accept being judged on next year.

Approach
  1. The probe is whether you can reason counterfactually about your own work, which is the same discipline this domain demands of you for programmes, applied where it is uncomfortable.
  2. State the counterfactual for each item: what would have happened without you. A measure specification that changed how a contract settles has a dollar counterfactual you can compute. A dashboard's counterfactual is analyst hours, which is real and small, and attaching a revenue number to it is where these accounts usually turn into fiction.
  3. Treat the killed programme as your strongest item and say why. Avoided spend is real value, it is attributable because the decision turned on your evaluation, and it is the one item nobody else will count on your behalf.
  4. Report the shipped model the way you would report anyone's model: calibration in the subgroups that matter, adoption by the people it was built for, and whether any decision changed. A model that is live but ignored has zero impact, and saying so is the credibility test in this answer.
  5. Name the failed project with its mechanism and its cost, then say what earlier signal you would watch to kill it sooner. Time to kill is a legitimate impact measure.
  6. Choose next year's number so that it can go down. A metric that only ratchets upward is not a commitment.
Follow-up
  • Two other people also claim the contract measure. How do you split it?
  • Your model is live and used, but the decisions it informs would have been the same without it. Is that impact?
  • What is the strongest argument that your year had less impact than you just described?

Explain an incomplete cost series to a non-technical executive

medium
claims runoutuncertaintyexecutive communication

An executive opens a dashboard showing risk-adjusted allowed PMPM down 6 percent across the last three incurred months and asks whether the cost initiative is working. You know pharmacy adjudicates within days, professional claims within weeks, and inpatient facility claims over months, so those three months are both undercounted and mix-shifted toward cheap services. There is also a genuine movement of roughly 1.5 percent in the older, complete months. Deliverable: a two-minute spoken answer, the change you make to the chart, and what you commit to telling them and when.

Approach
  1. The probe is whether you can be honest about uncertainty without sounding evasive. Executives read hedging as not knowing, so the answer has to end in a commitment.
  2. Separate the two claims immediately. The 6 percent is an artefact of incomplete data, and there is a smaller real movement in the months that are complete. Delivering only the debunk leaves them holding nothing.
  3. Explain the lag in their terms: the bills for the most expensive care arrive last, so an incomplete month always looks cheap and always looks like it is improving. Keep the phrase completion factor out of the first pass.
  4. Fix the chart instead of explaining around it. Shade or omit the incomplete months, print the paid-through date on the axis, and overlay the same series as it looked at equivalent maturity a year earlier so the shape is comparable rather than merely lower.
  5. Close with a date and a magnitude. Commit to a restated figure once runout matures, say roughly how far you expect the 6 percent to shrink, and name what you would need to see to call the initiative working.
Follow-up
  • They ask for your best guess today, knowing it is provisional. What do you say?
  • The restated number comes back at 1 percent. How do you handle having flagged the 6 percent at all?
  • How do you stop this dashboard producing the same conversation next quarter?
  • 01

    Describe a situation where your initial analysis or hypothesis was proven wrong. How did you pivot and communicate this to your team?

  • 02

    You are asked to account for a year of your work. Constraint: you may only use measures that existed before you knew the outcome, and you must include one project that moved nothing. The portfolio contains a measure specification that changed how a contract settles, a predictive model that shipped, a self-serve dashboard, and an evaluation that killed a proposed programme. Deliverable: how you attribute value to each, which of them you claim credit for and which you do not, and the one number you would accept being judged on next year.

  • 03

    An executive opens a dashboard showing risk-adjusted allowed PMPM down 6 percent across the last three incurred months and asks whether the cost initiative is working. You know pharmacy adjudicates within days, professional claims within weeks, and inpatient facility claims over months, so those three months are both undercounted and mix-shifted toward cheap services. There is also a genuine movement of roughly 1.5 percent in the older, complete months. Deliverable: a two-minute spoken answer, the change you make to the chart, and what you commit to telling them and when.

PracHub interview preparation framework ↗
Is this an official Tempus AI interview guide?

No. It is PracHub's own research and practice material for the Data Scientist role at Tempus AI. Rounds and questions reflect what candidates have reported, not a process Tempus AI has published, and they change over time. Confirm the current format and scope with your recruiter.

PracHub interview research ↗
How difficult is the technical take-home assignment?

The take-home challenge is known to be rigorous and time-consuming, often requiring multiple hours over a few days. It is designed to test your coding style, adherence to conventions, and scientific reasoning using realistic biomedical data, so plan your schedule accordingly.

PracHub interview research ↗
What is the typical timeline for the interview process?

The timeline can vary; some candidates experience a smooth, rapid multi-week loop, while others report a more deliberate pace involving recruiter screens, hiring manager chats, and thorough technical reviews. Maintaining proactive communication with your recruiter helps keep momentum.

PracHub interview research ↗
Are remote work options available for this role?

While many positions are aligned with primary hubs such as Chicago, Boston, New York, or San Francisco, certain roles offer hybrid or remote flexibility depending on the specific team and geographic jurisdiction. Always confirm current location policies with your recruiter during the initial screen.

PracHub interview research ↗
What differentiates successful candidates in the onsite rounds?

Successful candidates distinguish themselves not only by writing clean, modular code and solving technical problems accurately, but also by demonstrating clear scientific curiosity and the ability to explain complex methods to non-technical stakeholders with poise.

PracHub interview research ↗
Sources & methodology 3 sources ↗

No official company page is cited. Rounds and questions come from candidate reports and PracHub editorial material; each source shows the date it was read.